Panasept
employs two basic tools to provide superior soft contact lens
care: Micro
filtration
and Hydrogen
Peroxide. |
MICRO
FILTRATION:
The heart of the Panasept system is the unique Purifier. This device
makes the on-site preparation of freshly hydrated products practical. |
| The
Purifier houses a very durable 0.2 micron filter that maintains
an absolute barrier against all self propagating micro-organisms.
Panasept purifier is designed to be used only with ozonated or distilled
water*. Failure to do so will result in a prematurely plugged filter.
If the filter becomes plugged,
the purifier will no longer allow solution to be discharged. |
| *Viruses
are removed from water by the process of water distillation, reverse
osmosis and oxidation (e.g. ozonation). Water that has not been
treated by at least one of these treatments should not be used with
the Panasept Purifier. |
| If
properly used the Panasept Purifier is guaranteed to deliver fail-safe
operation for 1 year. |
| The
spout of the Purifier is equipped with a special one way valve that
prevents any air-born contaminates from entering the device. Once
solution has passed through the sterilizing filter, it cannot flow
back inside. Unlike squeeze bottles, which inhale debris after
use, the solution from a Panasept Purifier remains completely free
of contaminants. The Panasept Purifier is additionally equipped
with a filter that removes contaminants from the air that flows
into the storage tank to replace liquid that has been pumped out. |
HYDROGEN
PEROXIDE:
(natures disinfectant)
Hydrogen peroxide is continuously being created, neutralized and
controlled by our bodies for the maintenance of many physiological
processes. Hydrogen peroxide is a very versatile molecule that is
used for its disinfecting properties in many regions of the body.
There are multitudes of factors that affect its biocidal efficiency
therein. |
| Transition
metal ions greatly increase the germicidal activity of hydrogen
peroxide. They facilitate the catalytic conversion of hydrogen peroxide
into the very volatile hydroxyl ion. This is the mechanism by which
bacteria are destroyed. |
| Metal
ions on the outer bacterial surfaces provide the sites for this
catalytic conversion. Hydrogen peroxide kills bacteria very well,
provided that these metalo-sites are not insulated by the presence
of organic acids. |
| Panasept
delivers freshly made solution. The phosphoric acid within the H2O2
solution is diluted to one thousandth of its original concentration.
Consequently, bacteria are eliminated very effectively. Panasept
passes the Stand Alone Disinfection requirements for all challenge
organisms without the need for a separate neutralizing solution. |
| An important
characteristic of hydrogen peroxide is that it evaporates slowly.
Evaporated hydrogen peroxide leaves a residue for several hours
before it completely dissipates. Micro-biological tests show that
the germicidal activity of Panasept is increased by over one hundred
times by the simple process of evaporation. This is how the lens
case and the spout of the Purifier are kept germ free with the Panasept
system. |
| The
front surface of the eye is well equipped with the neutralizing
enzymes and ascorbates to provide protection from free radicals.
Panasept uses concentrations of hydrogen peroxide well tolerated
by the eye. |
SODIUM
BICARBONATE:
The dissolving of sodium percarbonate in water produces sodium bicarbonate
normally thought of as baking soda. Sodium bicarbonate is one of
the essential components for human life. Sodium bicarbonate is generated
within specific tissues of the body with the help of an enzyme called
carbonic anhydrase. The major roles of sodium bicarbonate include
the regulation of pH, the re-absorption of sodium and the removal
of carbon dioxide from the blood stream. |
| On the
surface of the eye, sodium bicarbonate is required for the regulation
of pH and the hydration of the mucin. Without the bicarbonate ion
mucin loses its ability to spread smoothly over the pre-corneal
tear film causing dry eye. Sodium bicarbonate with its cleansing
action, is perfectly suited for contact lens care. |
| THROUGH
THE STRATEGIC APPLICATION OF NATURALLY OCCURRING SUBSTANCES, PANASEPT
IS ABLE TO ACHIEVE SUPERIOR SAFETY AND COMFORT FOR ALL CONTACT LENS
WEARERS. |
-
DISADVANTAGES OF COMMONLY USED CHEMICALS IN OTHER PRODUCTS - |
POLYMERIC
DISINFECTANTS:
Polymeric disinfectants are sticky compounds that adhere to both
plastic and bacterial surfaces. These synthetic products are mildly
effective against some pathogenic organisms but there are many resistant
strains. These survivors often cling to the surfaces of the lens
case and secrete a protective layer, referred to as bio-film. Polymeric
disinfectants are large molecules that do not penetrate bio-film.
They simply adhere to the surface and serve as nutrients for bacteria
as they provide a rich supply of short-chain hydrocarbons. In contrast,
hydrogen peroxide is a very small molecule that penetrates bio-film
very effectively.
-Polymeric disinfectants also adhere to contact lens surfaces. This
adherence changes the surface quality of the lens making it dry
and irritable to the eye. |
SURFACTANTS:
Surfactants are often used as cleaning agents in contact lens solutions.
Non-ionic surfactants are relatively non-irritating to the eye but
they do disrupt its tear film causing symptoms of dryness. |
BORON:
Sodium borate and boric acid are commonly used as buffering agents
for contact lens solutions. They release boron into solution and
consequently are classified as acute metabolic toxins. Boron interferes
with the anabolic enzyme pathways that are necessary for the production
of phospho-lipid membranes such as the corneal epithelium. Boron
is absorbed rapidly by all soft tissues and is released very slowly.
For these reasons, boron releasing agents are not allowed for any
food processing. On the eye, long term exposure will lead to dryness,
contact lens intolerance and eventually corneal exhaustion. |
CITRATE:
As part of the Krebs cycle, citrate is essential to all aerobic
organisms; however, its presence on the surface of the eye may cause
a variety of undesirable effects. Tears normally contain five parts
per-million (ppm) of citrate, less than one fifth of the concentration
found in blood plasma.
One very commonly used contact lens solution has been found to contain
3600 ppm of citrate. The manufacturer claims that citrate at this
concentration, has protein removal properties. Unfortunately, it
may also be linked to the weakening of the tight junctions of the
epithelial cells of the cornea. Interestingly, citrate at concentrations
very close to this level is used as a skin exfoliant. Weakened tight
junctions of the corneal epithelium may lead to the development
of infiltrates and potentially, corneal ulceration. |
SUMMARY:
Only Panasept works in harmony with the natural defense mechanisms
of the eye. |
| The
chart below shows the constituents of Panasept in comparison to
human tears and two commercially available lens care products. |
|
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Copyright
© 2000-2005 Panasept
Manufacturing Corp.
All Rights Reserved |
|
